Medicines are sometimes prescribed for needs other than All those listed in the Medication Manual. Don't use Depakote to get a issue for which it was not prescribed. Never give Depakote to Others, whether or not they may have precisely the same signs or symptoms that you have. It could damage them.
Sufferers stabilized on rufinamide in advance of being prescribed valproate really should get started valproate therapy at a low dose, and titrate to a clinically successful dose [see DRUG INTERACTIONS].
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are using it to prevent migraine head aches and therefore are both pregnant or could grow to be Expecting since you aren't utilizing successful start Command (contraception).
are allergic to divalproex sodium, valproic acid, sodium valproate, or any of the components in Depakote. Begin to see the stop of this Medication Tutorial for a whole listing of components in Depakote. have a genetic trouble named a urea cycle disorder.
Your healthcare provider might decrease your dose, briefly quit, or forever end treatment For those who have specified Unintended effects.
This is especially crucial for Women of all ages organizing a pregnancy and for women at the onset of puberty; substitute therapeutic solutions needs to be viewed as for these people [see Boxed Warning and Use in Particular Populations (8.1)]. To forestall major seizures, valproate should not be discontinued abruptly, as This will precipitate position epilepticus with ensuing maternal and fetal hypoxia and danger to life. Evidence suggests that folic acid supplementation before conception and during the primary trimester of pregnancy decreases the chance for congenital neural tube defects in the final inhabitants. It is not known no matter whether the chance of neural tube defects or lowered IQ while in the offspring of ladies acquiring valproate is lessened by folic acid supplementation. Dietary folic acid supplementation the two before conception and during pregnancy ought to be routinely suggested for clients working with valproate.
Depakote delayed-launch tablets will also be employed to treat manic episodes related to bipolar disorder.
These highlights usually do not website contain all the information needed to use Depakote securely and properly. See whole prescribing information and facts for Depakote.
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Carcinogenesis Valproate was administered orally to rats and mice at doses of eighty and one hundred seventy mg/kg/day (under the utmost suggested human dose on a mg/m2 foundation) for 2 several years.
are male and decide to father a youngster. DEPAKOTE might induce fertility difficulties, which can have an effect on your power to father a baby. Check with your healthcare supplier if this is a difficulty in your case.
medicine residue with your stool. Notify your Health care service provider When you have or Feel maybe you have medication residue as part of your stool.